Erythropoietin couples hematopoiesis with bone formation.
It is well established that bleeding activates the hematopoietic system to regenerate the loss of mature blood elements.We have shown that hematopoietic stem cells (HSCs) isolated from animals challenged with an acute bleed regulate osteoblast differentiation from marrow PL-L LEd Replacements stromal cells.This suggests that HSCs participate in bon